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Hitoshi Shimada Selected Research

Nortriptyline (Aventyl)

4/2014Norepinephrine transporter occupancy by nortriptyline in patients with depression: a positron emission tomography study with (S,S)-[¹⁸F]FMeNER-D₂.

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Hitoshi Shimada Research Topics

Disease

16Alzheimer Disease (Alzheimer's Disease)
01/2022 - 03/2010
9Dementia (Dementias)
09/2020 - 06/2012
8Cognitive Dysfunction
01/2022 - 06/2012
5Tauopathies
01/2019 - 06/2012
4Amyloid Plaque
06/2020 - 09/2013
3Major Depressive Disorder (Major Depressive Disorders)
10/2021 - 06/2013
3Corticobasal Degeneration
10/2015 - 07/2010
2Parkinsonian Disorders (Parkinsonism)
09/2020 - 01/2019
2Parkinson Disease (Parkinson's Disease)
09/2020 - 06/2012
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 01/2018
2Hypoglycemia (Reactive Hypoglycemia)
01/2019 - 12/2012
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2019 - 03/2018
2Atrophy
01/2019 - 02/2013
2Neoplasms (Cancer)
01/2018 - 06/2013
2Disease Progression
01/2014 - 02/2013
2Hypertension (High Blood Pressure)
08/2013 - 06/2008
2Frontotemporal Dementia (Semantic Dementia)
07/2010 - 07/2010
1Coronary Artery Disease (Coronary Atherosclerosis)
10/2021
1Chronic Renal Insufficiency
10/2021
1Autism Spectrum Disorder
11/2020
1REM Sleep Behavior Disorder
09/2020
1Synucleinopathies
09/2020
1Tremor (Tremors)
09/2020
1Febrile Neutropenia
01/2018
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018
1Diarrhea
01/2018
1Pneumonia (Pneumonitis)
01/2018
1Hypertriglyceridemia
01/2018
1Mental Disorders (Mental Disorder)
12/2017
1Primary Progressive Aphasia
10/2015
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
04/2014
1Hypoxia (Hypoxemia)
02/2013
1Lewy Body Disease (Lewy Body Dementia)
02/2013
1Atherosclerosis
12/2012
1Hyperglycemia
12/2012
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
07/2010
1Pallidopontonigral Degeneration
07/2010
1Shock
04/2010
1Thymoma (Thymic Carcinoma)
06/2008
1Encephalitis (Encephalitis, Rasmussen)
06/2008
1Isaacs Syndrome (Neuromyotonia)
06/2008

Drug/Important Bio-Agent (IBA)

13Amyloid (Amyloid Fibrils)IBA
01/2022 - 06/2012
5AcetylcholinesteraseIBA
01/2018 - 03/2010
52- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA
01/2017 - 02/2012
4LigandsIBA
10/2021 - 09/2013
4Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA
11/2020 - 06/2013
3Proteins (Proteins, Gene)FDA Link
06/2020 - 06/2012
3Biomarkers (Surrogate Marker)IBA
01/2020 - 06/2012
2benzothiazoleIBA
01/2019 - 01/2017
2Insulin (Novolin)FDA Link
01/2019 - 12/2012
2Cholinergic Agents (Cholinergics)IBA
01/2018 - 07/2010
2Acetates (Acetic Acid Esters)FDA Link
07/2010 - 03/2010
1Biological ProductsIBA
01/2022
1AZD5718IBA
10/2021
15-Lipoxygenase-Activating ProteinsIBA
10/2021
1Dopamine (Intropin)FDA LinkGeneric
11/2020
1Norepinephrine (Noradrenaline)FDA LinkGeneric
11/2020
1Dopamine D1 Receptors (Dopamine D1 Receptor)IBA
11/2020
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
09/2020
1Levodopa (L Dopa)FDA LinkGeneric
09/2020
1Flavin-Adenine Dinucleotide (FAD)IBA
06/2020
1Apolipoprotein E4IBA
01/2019
1Antipsychotic Agents (Antipsychotics)IBA
01/2019
1Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2019
1Glucose (Dextrose)FDA LinkGeneric
01/2019
1Indicators and Reagents (Reagents)IBA
03/2018
1AZD 6244IBA
01/2018
1Docetaxel (Taxotere)FDA Link
01/2018
1Alanine Transaminase (SGPT)IBA
01/2018
1Carboxylic AcidsIBA
01/2018
1Docosahexaenoic AcidsIBA
01/2018
1Eicosapentaenoic AcidIBA
01/2018
1Amyloid beta-PeptidesIBA
01/2018
1Complex MixturesIBA
01/2018
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
10/2015
1AminesIBA
06/2014
1Nortriptyline (Aventyl)FDA LinkGeneric
04/2014
1SynucleinsIBA
01/2014
1Pharmaceutical PreparationsIBA
01/2014
1BenzothiazolesIBA
09/2013
1Hormones (Hormone)IBA
08/2013
1Fentanyl (Sublimaze)FDA LinkGeneric
08/2013
1Serotonin (5 Hydroxytryptamine)IBA
06/2013
1(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
06/2013
1Milnacipran (Ixel)FDA Link
06/2013
1Mechanistic Target of Rapamycin Complex 1IBA
06/2013
1gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
02/2013
1saracatinibIBA
02/2013
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
02/2013
1Complement System Proteins (Complement)IBA
06/2012
1Dihydroxyphenylalanine (Dopa)IBA
07/2010
1N-methylpiperidin-4-yl acetateIBA
07/2010
1DAA 1106IBA
07/2010
1Anesthetics (Anesthetic Agents)IBA
04/2010
1landiololIBA
04/2010
1Donepezil (Aricept)FDA LinkGeneric
03/2010
1Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
06/2008

Therapy/Procedure

4Therapeutics
01/2019 - 06/2008
1General Anesthesia
08/2013
1Anesthesia
08/2013